AKG Capsules

Alpha ketoglutarate (-KG) yog ib qho tseem ceeb metabolic nruab nrab ntawm lub voj voog tricarboxylic acid (TCA lub voj voog lossis citric acid voj voog) hauv cov kab mob microbial. Nws nyob tom qab isocitrate thiab ua ntej succinyl CoA, ua lub luag haujlwm tseem ceeb hauv kev sib txuas cov pa roj carbon metabolism thiab nitrogen metabolism hauv cov txheej txheem no. Tshwj xeeb, hauv TCA lub voj voog, thaum isocitrate yog catalyzed los ntawm isocitrate dehydrogenase los tsim alpha ketoglutarate, nws tsis tsuas yog ua tiav qhov kev hloov ntawm C5 compound mus rau C4 compound, tab sis kuj muab cov khoom tsim nyog substrate rau cov kauj ruam tom ntej.
Raws li cov khoom tseem ceeb nodal, qhov concentration ntawm - ketoglutarate ncaj qha cuam tshuam rau kev ua haujlwm ntawm tag nrho TCA lub voj voog. Txhawm rau kom muaj kev ruaj ntseg ntawm qib alpha ketoglutarate, muaj ntau lub zog ntxiv hauv cov hlwb kom ntxiv cov metabolite tseem ceeb hauv nruab nrab. Ib txoj hauv kev yog los ntawm kev hloov pauv ntawm glutamic acid: siv glutamic acid ua ib qho amino pub, nyob rau hauv qhov kev txiav txim ntawm cov enzymes tshwj xeeb, feem ntau glutamate dehydrogenase los yog glutaminase, cov amino pawg ntawm glutamic acid yog pauv mus rau alpha ketoglutarate, yog li tsim tshiab alpha ketoglutarate molecules. Cov txheej txheem no tseem ceeb heev rau kev ua kom muaj kev ua haujlwm tas mus li thiab muaj txiaj ntsig ntawm TCA lub voj voog.

Alpha ketoglutarate (AKG), uas yog ib qho tseem ceeb hauv metabolic nruab nrab, maj mam tau txais kev saib xyuas hauv kev ua kis las khoom noj khoom haus. Nws yog tsuas yog siv los ua cov khoom xyaw hauv cov khoom noj khoom haus kis las ncaws pob thiab ntseeg tias yuav muab kev txhawb zog ntxiv thiab txhawb kev rov qab los rau cov neeg ncaws pob.
Thaum lub sijhawm ua haujlwm hnyav, tib neeg lub cev siv ntau lub zog thiab tsim lactate thiab lwm yam khoom pov tseg. Kev sib sau ntawm cov khoom siv metabolic no tuaj yeem ua rau qaug zog thiab mob leeg. Alpha ketoglutarate, raws li lub zog substrate, tuaj yeem siv los ntawm cov leeg nqaij los pab tswj lub zog thiab ncua qhov tshwm sim ntawm qaug zog. Tsis tas li ntawd, nws tseem tuaj yeem txhawb nqa cov metabolism ntawm lactic acid, txo qhov sib xyaw ntawm lactic acid hauv cov leeg, thiab ntxiv cov leeg mob.
Ntxiv rau kev muab lub zog ncaj qha, alpha ketoglutarate kuj tseem tuaj yeem txhim kho kev ua kis las los ntawm lwm cov txheej txheem. Piv txwv li, nws tuaj yeem koom nrog hauv cov metabolism ntawm cov amino acids, txhawb cov protein synthesis, thiab pab txhawb kev kho cov leeg thiab kev loj hlob. Tsis tas li ntawd, qee qhov kev tshawb fawb tau pom tias alpha ketoglutarate kuj tseem muaj cov teebmeem antioxidant, txo cov kev ntxhov siab oxidative los ntawm kev tawm dag zog thiab tiv thaiv cov hlwb los ntawm kev puas tsuaj.

Txhawb zog metabolism:AKG yog ib qho tseem ceeb metabolic nruab nrab hauv lub voj voog tricarboxylic acid (TCA lub voj voog), koom nrog hauv cov txheej txheem ntawm kev tsim hluav taws xob. Thaum lub sijhawm ua haujlwm, AKG tuaj yeem siv los ntawm cov leeg nqaij los pab tswj lub zog thiab ncua qhov pib qaug zog.
Txhawb nqa rov qab:AKG pab txo cov leeg mob tom qab qoj ib ce los ntawm kev txhawb nqa lactate metabolism thiab txo qis lactate tsub zuj zuj hauv cov leeg.
Protein synthesis:AKG koom nrog cov metabolism hauv cov amino acids, txhawb kev tsim cov protein, thiab muaj txiaj ntsig zoo rau kev kho cov leeg nqaij thiab kev loj hlob.
Antioxidant nyhuv:Qee cov kev tshawb fawb qhia tias AKG kuj tseem tuaj yeem muaj cov khoom antioxidant, txo cov oxidative kev ntxhov siab los ntawm kev tawm dag zog thiab tiv thaiv cov hlwb los ntawm kev puas tsuaj.
Kev tiv thaiv ammonia lom:Hauv qee qhov tshwj xeeb, xws li cov neeg mob raum, vim yog lub raum tsis ua haujlwm, ammonia tsis tuaj yeem tshem tawm tau zoo. AKG tuaj yeem ua ke nrog ammonia los tsim cov khoom tsis muaj tshuaj lom, yog li txo cov tsos mob ntawm ammonia lom.